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Peer-reviewed veterinary case report

Cryosurgery to treat skin tumors in dogs and cats

By De Queiroz, Genilson Fernandes et al.·Published in Veterinary surgery : VS·2008·Department of Surgery, Brazil·View original on PubMed

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Original publication title: Clinical study of cryosurgery efficacy in the treatment of skin and subcutaneous tumors in dogs and cats.

Plain-English summary

A group of dogs and cats with skin or subcutaneous tumors underwent cryosurgery, a treatment that uses extreme cold to destroy the tumors. The procedure involved applying liquid nitrogen to the tumors for a short time, with most pets experiencing minimal complications like swelling or redness. After treatment, 98% of the tumors did not return, and the pets healed well over time. This method is particularly useful for older pets where traditional surgery might be more challenging.

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Abstract

OBJECTIVE: To evaluate the efficacy of cryosurgery for treatment of skin and subcutaneous tumors in dogs and cats. STUDY DESIGN: Prospective study. ANIMALS: Dogs (n=20), cats (10). METHODS: Cutaneous or subcutaneous tumors were treated by liquid nitrogen cryosurgical spray (1 cm from target tissue at 90 degrees until a 5-mm halo of frozen tissue was achieved) for 15-60 seconds. Malignant lesions had 3 freeze-thaw cycles benign tumors, 2 cycles. The second or third freeze cycle was performed after complete thaw of the preceding freeze. Wounds healed by second intention. Follow-up was weekly for 1 month and then twice monthly until wounds healed, and final outcome was determined by telephone interview of owners. RESULTS: Tumor size ranged from 0.3 to 11 cm diameter with 28 (60%) being 0.3-1 cm; 8 (17%) 1.1-3 cm, and 11 (23%) >3.4 cm. Complications included edema, erythema and for extremity lesions, pain and lameness. Treated lesions (n=47) had an overall remission of 98% (mean follow-up, 345+/-172.02 days [range, 150-750 days]). One malignant peripheral nerve sheath tumor recurred 7 months after cryosurgical treatment. CONCLUSION: Cryosurgery is an efficient method for treatment of skin and subcutaneous tumors in dogs and cats. CLINICAL RELEVANCE: Cryosurgical ablation is an effective means of treating small cutaneous or subcutaneous tumors in dogs and cats, especially in older animals where wound closure or cosmetic outcome might limit surgical excision alone.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18986310/