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Peer-reviewed veterinary case report

How ELISA blood test detects Babesia gibsoni infection in dogs

By Miyama, Takako et al.·Published in The Journal of veterinary medical science·2006·Faculty of Agriculture, Japan·View original on PubMed

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Original publication title: Clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50.

Species:
dog

Plain-English summary

A group of dogs in an area where Babesia gibsoni infection is common was tested for the disease using a blood test called ELISA. Out of 14 dogs with a recent infection, only 8 tested positive, which suggests that the test might miss some cases. However, all 14 dogs that had previously been infected and were anemic tested positive, indicating that the test is more reliable for detecting past infections. This means that while the test may not always catch new infections, it can confirm if a dog has had the disease before.

People also search for: dog Babesia gibsoni symptoms · dog anemia treatment · Babesia infection test for dogs

Abstract

The clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50 was examined in dogs in an area where B. gibsoni infection was endemic. Only 8 among 14 dogs with acute type B. gibsoni infection without a previous history of infection were positive. This high percentage of false-negative results is thought to be a weak point of ELISA as a diagnostic tool. However, 14 other anemic dogs with a confirmed history of B. gibsoni infection were all positive, thus confirming the higher sensitivity of ELISA in detecting a history of infection.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17213713/