Peer-reviewed veterinary case report
Using fructosamine blood tests to diagnose and monitor diabetes
By Thoresen, S. I. & Bredal, W. P.·Published in Journal of Small Animal Practice·1996·View original on Crossref →
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Original publication title: Clinical usefulness of fructosamine measurements in diagnosing and monitoring feline diabetes mellitus
- Species:
- cat
Plain-English summary
A group of diabetic cats was tested to see how well fructosamine levels in their blood could help diagnose and monitor their condition. The study included cats with recent symptoms and those that had been treated with insulin. It found that untreated diabetic cats had high fructosamine levels, while those on insulin showed varying levels of control based on their fructosamine results. This test can help veterinarians understand how well a cat's diabetes is being managed and whether adjustments to treatment are needed.
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Abstract
ABSTRACTFructosamines are glycated serum proteins that reflect long‐term serum glucose concentrations in humans and several animal species. In the present study, blood samples were drawn from three populations of diabetic cats: untreated diabetic cats with clinical symptoms prevailing only a few days (n = 1), untreated diabetic cats with symptoms lasting more than two weeks (n = 6) and clinically well stabilised diabetic cats receiving insulin twice daily which showed no signs of disease (n = 4). All untreated diabetic cats showed elevated fructosamine measurements. Based on fructosamine measurements, clinically well stabilised diabetic cats could be subdivided further according to the degree of glycaemic control. Diabetic cats with satisfactory glycaemic control revealed fructosamine concentrations within or close to the reference range (146 to 271 umol/litre), whereas fructosamine concentrations above 400 umol/litre indicated insufficient glycaemic control. This study suggests that the fructosamine assay reflects persistently elevated serum glucose concentrations in cats and is a useful parameter for diagnosing and monitoring diabetes mellitus in cats.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1748-5827.1996.tb01940.x