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Peer-reviewed veterinary case report

Heart function test results in cats with hypertrophic cardiomyopathy

By Naseri, A et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2026·Selcuk University·View original on PubMed

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Original publication title: Clinical value of the tissue Doppler derived index of myocardial performance (Tei index) in cats with hypertrophic cardiomyopathy.

Species:
cat

Plain-English summary

A group of 20 cats with hypertrophic cardiomyopathy (HCM), a heart condition that can cause breathing problems and lethargy, were examined to understand how their hearts were functioning. The study found that most of these cats had issues with both the contraction and relaxation of their heart muscles. While certain measurements indicated heart function problems, the overall performance index did not differ significantly from healthy cats. The researchers noted that lower heart motion speeds and higher breathing rates could be warning signs for serious health risks in these cats.

People also search for: cat heart disease symptoms · hypertrophic cardiomyopathy in cats · cat breathing problems treatment

Abstract

INTRODUCTION/OBJECTIVES: The aim of the present study was to investigate the left ventricular Index of Myocardial Performance (IMP) by tissue Doppler echocardiography in cats with hypertrophic cardiomyopathy (HCM). ANIMALS, MATERIALS AND METHODS: Twenty cats with HCM and 10 healthy cats were included in the study. Clinical examination, electrocardiography, blood pressure measurement, thoracic radiography and transthoracic echocardiography were performed in both healthy and HCM cats. Left ventricular IMP was assessed by tissue Doppler imaging (TDI) echocardiography. RESULTS: Systolic dysfunction was observed in 11 cats (55 %), and diastolic dysfunction was present in all cats with HCM. Although the isovolumic contraction time (IVCT) and ejection time (ET) were significantly shorter in cats with HCM, the IMP was not significantly different between the study groups. Peak velocity of early diastolic mitral annular motion as determined by pulsed wave Doppler (E') and respiratory rate (RR) were identified as potential predictors of mortality. STUDY LIMITATIONS: Small sample size and lack of time-adjusted survival analysis may reduce the strength of prognostic conclusions. CONCLUSIONS: Our study shows that both diastolic and systolic dysfunction are present in cats with HCM and that these alterations affect left ventricular IMP, potentially limiting its clinical applicability. Furthermore, low E' and increased RR were identified as potential predictors of mortality in cats with HCM.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41499857/