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Peer-reviewed veterinary case report

Cloprostenol treatment for open-cervix pyometra in cats

By García Mitacek, María C et al.Ā·Published in Journal of feline medicine and surgeryĀ·2014Ā·Faculty of Veterinary ScienceĀ·View original on PubMed →

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Original publication title: Cloprostenol treatment of feline open-cervix pyometra.

Species:
cat
Stomach & digestionCats

Plain-English summary

A group of five female cats with open-cervix pyometra (a serious uterine infection) were treated with cloprostenol, a medication that helps the uterus contract, along with amoxicillin, an antibiotic. After receiving the treatment, the cats experienced some mild side effects like diarrhea and vomiting shortly after the injections, but these symptoms were temporary. All the cats showed improvement and remained healthy for a year after treatment, with most returning to normal heat cycles and two even having healthy litters. Cloprostenol proved to be an effective option for treating this condition in cats.

People also search for: cat pyometra treatment Ā· cloprostenol for cats Ā· cat vomiting after injection Ā· feline uterine infection symptoms

Abstract

Treatment with cloprostenol, a prostaglandin synthetic analogue, was evaluated in five queens with open-cervix pyometra. Cloprostenol was administered (5 μg/kg body weight SC) on 3 consecutive days and amoxicillin (20 mg/kg body weight IM) on 7 consecutive days. Transient post-injection reactions caused by cloprostenol administration included diarrhea, vomiting and vocalizations. Reactions began as quickly as 10 mins after cloprostenol administration and lasted as long as 30 mins. All queens improved clinically after cloprostenol treatment and remained healthy until the end of the study, 1 year after treatment. All queens resumed normal estrous cycles without further treatment and two (40%) delivered a normal litter. In conclusion, use of cloprostenol is an acceptable treatment for open-cervix pyometra in queens.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23884637/