Peer-reviewed veterinary case report
Dog given six times closantel dose with blindness and liver damage
By McEntee, K et al.·Published in Veterinary and human toxicology·1995·Small Animal Clinic·View original on PubMed →
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Original publication title: Closantel intoxication in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought in after accidentally receiving six times the recommended dose of a medication called closantel. The dog showed serious symptoms, including vision problems, hearing loss, liver damage, and muscle weakness. The vet treated the dog with albumin to help reduce the toxicity from the medication. While the dog recovered from most of the symptoms, unfortunately, the blindness caused by the overdose was permanent.
People also search for: dog closantel overdose treatment · why is my dog blind · dog liver damage symptoms
Abstract
A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended dosage. Closantel induced optic neuritis, retinal degeneration, partial deafness, hepatotoxicosis and myopathy. Only the blindness was irreversible. The therapy included albumin administration to reduce the acute toxicity of closantel.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7571353/