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Peer-reviewed veterinary case report

Dogs with recurring diarrhea from C. difficile improve after diet

By Silva, Rodrigo Otávio Silveira et al.·Published in Anaerobe·2018·Veterinary School, Brazil·View original on PubMed

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Original publication title: Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes.

Species:
dog

Plain-English summary

Five dogs with ongoing diarrhea were found to have a Clostridioides difficile infection, but they didn't get better with the usual medication, metronidazole. One dog had a colonoscopy that showed inflammation in the colon. However, all five dogs fully recovered after their owners changed their diets. This case highlights that dogs with persistent diarrhea and a positive test for C. difficile might have other underlying gut issues that need to be addressed.

People also search for: dog chronic diarrhea treatment · Clostridioides difficile in dogs · dietary changes for dog diarrhea · dog eosinophilic colitis · metronidazole for dog diarrhea

Abstract

Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely recovered after dietary changes. The present work suggests that CDI might occur in dogs with other intestinal alterations. In addition, this report suggests that dysbiosis should be considered in animals that have chronic-recurring diarrhea and test positive for C. difficile.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29621604/