Peer-reviewed veterinary case report
Cobalt-Catalyzed C-Se Bond Activation: Cross-Coupling of Organoselenides with Grignard Reagents.
- Year:
- 2025
- Authors:
- de Souza Pinto TV et al.
- Affiliation:
- Laboratório de Pesquisa de Produtos Naturais · Brazil
Abstract
Herein, we report a cobalt-catalyzed cross-coupling of organoselenides with Grignard reagents using simple CoCl<sub>2</sub> as the catalyst. This efficient method accommodates a broad scope of selenides, including vinyl, aryl, heteroaryl, and alkynyl derivatives, under mild and ligand-free conditions. Remarkably, the reaction proceeds efficiently without additives and afforded the desired products in moderate to good yields within just 3 h.
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Search related cases →Original publication: https://europepmc.org/article/MED/41226192