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Peer-reviewed veterinary case report

Heart base mass caused by coccidioidomycosis in two dogs

By Ajithdoss, D K et al.·Published in Journal of comparative pathology·2011·Department of Veterinary Pathobiology, United States·View original on PubMed

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Original publication title: Coccidioidomycosis presenting as a heart base mass in two dogs.

Species:
dog

Plain-English summary

Two dogs were diagnosed with coccidioidomycosis, a fungal infection, that presented as masses at the base of their hearts. One dog had a large mass that was pressing on important blood vessels and airways, which was confirmed through imaging tests. Unfortunately, both dogs were found to have severe inflammation and fungal spherules in the heart tissue during necropsy. This case highlights a rare instance where a fungal infection mimicked a heart tumor in dogs.

People also search for: dog heart mass symptoms · coccidioidomycosis in dogs · dog heart problems treatment

Abstract

Two atypical cases of canine coccidioidomycosis presenting as heart base masses are described. An echocardiogram performed in one of the two dogs revealed a large mass at the base of the heart and a computed tomography scan showed that the mass compressed the bronchi, left atrium, aorta and pulmonary arteries. A firm, white or pale yellow mass was found at the base of the heart at necropsy examination in both cases. Microscopical examination of the masses revealed severe, chronic, locally extensive granulomatous or pyogranulomatous inflammation with intralesional spherules consistent with Coccidioides spp. The diagnosis was further confirmed by immunohistochemistry and in-situ hybridization. Coccidioides spp. have been reported to cause pericarditis in dogs, but this is the first description of coccidioidomycosis mimicking a heart-based tumour in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21334001/