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Peer-reviewed veterinary case report

Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury.

Journal:
Fertility and sterility
Year:
2010
Authors:
Erol, Bulent et al.
Affiliation:
Department of Urology
Species:
rodent

Abstract

In this experimental study, we assessed the preventive effects of coenzyme Q(10) (CoQ(10)) in a rat model of ischemia/reperfusion injury. The results of this study show that CoQ(10) administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19683231/