Peer-reviewed veterinary case report
Colistin Resistance Geneand Its Variant in Escherichia coli Isolates from Chickens in China.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2017
- Authors:
- Yang, Yong-Qiang et al.
- Affiliation:
- College of Life Science · China
Abstract
Thegene was detected in 5.11% (58/1136) ofisolates of chicken origin from 13 provinces in China. A novelvariant, named, encoding an Ile-to-Val functional variant of MCR-1 was identified in a sequence type 155 (ST155) strain. An-containing IncI2 plasmid, pHeN867 (60,757 bp), was identified. The transfer of pHeN867 led to a 32-fold increase in the MIC of colistin in the recipient, exhibiting an effect on colistin resistance that was similar to that of.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28242671/