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Peer-reviewed veterinary case report

Rare liver cancer combining two types in a 12-year-old Yorkshire

By Shiga, A et al.Ā·Published in The Journal of veterinary medical scienceĀ·2001Ā·Department of Veterinary Pathology, JapanĀ·View original on PubMed →

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Original publication title: Combined hepatocellular and cholangiocellular carcinoma in a dog.

Species:
dog

Plain-English summary

A 12-year-old male Yorkshire terrier was diagnosed with a rare type of liver cancer that included both liver and bile duct cancer cells. The tumor was unique because it had features that helped differentiate it from other types of liver tumors. Unfortunately, this type of cancer is quite uncommon in dogs, and the specific treatment details or outcomes were not provided. If your dog shows signs of illness, it's important to consult your veterinarian for a proper diagnosis and treatment plan.

People also search for: dog liver cancer symptoms Ā· Yorkshire terrier cancer treatment Ā· signs of dog bile duct problems

Abstract

A transitional type of combined hepatocellular and cholangiocellular carcinoma developed in a 12-year-old male Yorkshire terrier dog. The tumor was histologically composed of both hepatocellular carcinoma and cholangiocellular carcinoma components, and both elements were closely intermingled. Intraluminal mucin accumulation in cytokeratin-positive tubular/glandular structures was observed within the cholangiocellular carcinoma components and this feature was useful histological marker for a differential diagnosis between combined hepatocellular and cholangiocellular carcinoma and a pseudoglandular type of hepatocellular carcinoma. This primary hepatic tumor is extremely rare in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11346190/