Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention

Abstract

Background: Environmental changes affecting pet animals, along with an increase in age-related conditions and diseases among pets, have become increasingly evident. Despite this trend, there remains a paucity of research on therapeutic approaches for geriatric companion animals. Case Description: The case report describes a 19-year-old spayed female cat that was diagnosed with chronic renal failure and recurrent corneal disease. Surgical intervention was not pursued at the owner's request, leaving medical management as the only viable option. The patient's corneal condition deteriorated, culminating in corneal perforation. Upon initiation of equine placental extract supplementation alongside medical treatment, substantial improvements were observed in hyperaemia, ocular discomfort, and additional corneal manifestations, including wound severity, ocular discharge, photophobia, lacrimation, and blepharospasm. Conclusion: The integration of medical therapy with placental extract supplementation may represent a novel therapeutic alternative for geriatric cats ineligible for surgical intervention. [Open Vet. J. 2025; 15(10.000): 5420-5426]