Peer-reviewed veterinary case report
Comparing ORIHIME and Gynemesh PS Mesh in Laparoscopic Sacrocolpopexy
By Kuwata T et al.·2026·Daiichi Towakai Hospital, Japan·View original on Europe PMC →
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Original publication title: Comparable Performance of ORIHIME Mesh Versus Gynemesh PS in Laparoscopic Sacrocolpopexy: A Retrospective Comparative Study.
Plain-English summary
This study looked at two types of surgical mesh used in a procedure called laparoscopic sacrocolpopexy, which helps support the pelvic organs. Researchers compared the performance of a new mesh called ORIHIME, made from polytetrafluoroethylene, with a more commonly used mesh called Gynemesh PS, made from polypropylene. They followed 211 patients for two years after their surgeries and found that both types of mesh had similar outcomes in terms of complications and improvements in urinary symptoms. There was a slight difference in recurrence rates of pelvic organ prolapse, but it wasn't significant. Overall, the study suggests that ORIHIME mesh works just as well as the traditional option, but more research is needed to confirm these findings.
Abstract
<h4>Introduction</h4>In Japan, laparoscopic sacrocolpopexy (LSC) is performed using either the commonly used polypropylene (PP) mesh or the domestically produced polytetrafluoroethylene (PTFE) mesh, ORIHIME. Despite its clinical adoption, the comparable performance of this material relative to conventional options such as PP mesh has not been sufficiently investigated. This study aimed to compare clinical outcomes of LSC using PTFE mesh (ORIHIME) versus PP mesh (Gynemesh PS) through a retrospective study.<h4>Methods</h4>A total of 211 patients who underwent LSC at our hospital and for whom follow-up was possible up to the second postoperative year were enrolled. Eighty-six patients received PTFE mesh and 125 received PP mesh. We compared patient demographics, perioperative data, 2-year outcomes, complications, and improvements in subjective urinary symptoms between the two groups.<h4>Results</h4>Baseline characteristics were similar between the groups. One patient (1.2%) in the PTFE group experienced a Stage III cystocele recurrence 1 year postoperatively and required transvaginal mesh. The recurrence rate of POP-Q Stage II or higher at 2 years was 7.0% in the PTFE group and 4.8% in the PP group, with no statistically significant difference between groups. Improvements in subjective urinary symptoms over 24 months were similar in both groups, and no mesh-related or other postoperative complications were observed.<h4>Conclusions</h4>In this retrospective study with a two-year follow-up, LSC using PTFE mesh demonstrated clinical outcomes comparable to those achieved with PP mesh. These findings suggest that PTFE mesh may represent a reasonable alternative for LSC, although further prospective studies with longer follow-up are warranted.
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Search related cases →Original publication on Europe PMC: https://europepmc.org/article/MED/41744457