Comparative Accuracy of Dental Age Estimation Methods in Adolescents and Young Adults: A Systematic Review With Cameriere's Method as the Reference Standard.

Abstract

Dental age estimation is a crucial tool in forensic science, particularly for legal purposes where age verification is essential. This process helps distinguish minors from adults, influencing decisions in criminal, immigration, and civil matters. The Cameriere's Third Molar Maturity Index (I3M) is one of the reliable techniques for the assessment of age. After being retrieved from databases such as PubMed, Scopus, the Cochrane Library, and EBSCOhost, publications from 2013 to 2025 were screened against our inclusion criteria. As a result, five articles were included in the systematic review. The Newcastle-Ottawa scale (NOS) is used for the assessment of risk of bias of included studies, and meta-analysis was not possible due to the heterogeneity of selected studies in terms of methods of analysis. Results from the studies reviewed indicate that Cameriere's I3M is the most dependable method for dental age estimation in adolescents and young adults. Evidence from comparative analyses shows that I3M performs better than the London Atlas for individuals aged 14-22, and additional findings support its effectiveness across similar age ranges. Assessments based on root pulp visibility have also been reported to provide slightly higher accuracy in the 15-22 age group. Overall, the systematic review confirms that Cameriere's I3M remains the most reliable approach for estimating dental age in adolescents and young adults.