Peer-reviewed veterinary case report
Comparative efficacies of TAK-187, a long-lasting ergosterol biosynthesis inhibitor, and benznidazole in preventing cardiac damage in a murine model of Chagas' disease.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2005
- Authors:
- Corrales, Milagros et al.
- Affiliation:
- Laboratorio de Patologí
Abstract
We carried out a comparative study of benznidazole and TAK-187, a long-lasting ergosterol biosynthesis inhibitor, with a murine model of Chagas' disease. The results indicated that TAK-187 was more effective than benznidazole in preventing Trypanosoma cruzi-induced cardiac damage in experimental animals.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15793138/