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Peer-reviewed veterinary case report

Comparative Evaluation of Efficacy of Povidone-Iodine on Covid-19 Viral Load - A Systematic Review and Meta-Analysis.

Year:
2024
Authors:
Mallick SC et al.
Affiliation:
Department of Oral Medicine Diagnosis and Radiology · India

Abstract

<h4>Introduction</h4>To assess if povidone-iodine is a more effective mouthwash than other mouthwashes in treating COVID-19.<h4>Materials and methods</h4>The review was completed in compliance with PRISMA principles and entered into PROSPERO. Databases on electronic devices were examined. Using RevMan software version 5.3, the Cochrane risk of bias (ROB) -2 tool was employed for quality evaluation.<h4>Results</h4>When compared to other mouthwashes, povidone-iodine was shown to reduce the COVID-19 viral load on average by 0.11 (-0.67-0.44) times, however, this difference is not statistically significant.<h4>Conclusion</h4>Povidone-iodine was found to have a substantial impact on lowering the COVID-19 viral load in COVID-19 patients when compared to the control group. Povidone-iodine appears to be safer for long-term use, although both mouthwashes were equally effective.

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Original publication: https://europepmc.org/article/MED/40061702