Peer-reviewed veterinary case report
How well dinotefuran and imidacloprid kill fleas on cats
By Murphy, Martin et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2009·Charles River Laboratories Preclinical Services Ireland·View original on PubMed →
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Original publication title: Comparative in vivo adulticidal activity of a topical dinotefuran versus an imidacloprid-based formulation against cat fleas (Ctenocephalides felis) on cats.
- Species:
- cat
Plain-English summary
A group of cats was treated with either dinotefuran or imidacloprid to see which flea treatment worked better. Both treatments were applied once, and the cats were then infested with fleas to measure how many remained after treatment. The cats that received dinotefuran had significantly fewer fleas at various times compared to those treated with imidacloprid, especially in the first few days after treatment. This suggests that dinotefuran may be more effective for quickly reducing flea populations on cats.
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Abstract
Fleas cause significant discomfort to pet cats and distress to their owners and are also vectors of disease severe infestations can cause anemia or flea allergy dermatitis and can lead to infections with Dipylidium caninum and Bartonella henselae. Rapid flea kill is an important feature of flea preventives. The efficacy of dinotefuran (Vectra for Cats and Kittens, Summit VetPharm) was compared with that of imidacloprid (Advantage, Bayer Animal Health) against Ctenocephalides felis when applied topically once on day 0. Cats were infested with 100 (+-3) C. felis on study days -1, 8, 15, 22, and 29. Live fleas were counted on study days 0 (2, 6, and 12 hours after treatment), 9, 16, 23, 29 (2, 6, and 12 hours after infestation), and 30. Cats treated with dinotefuran had significantly (P less than .05) fewer fleas than the control cats at all posttreatment examinations except day 29 at 2 hours after infestation and significantly (P less than .05) fewel fleas than cats treated with imidacloprid on days 0 (2 hours after treatment), 9, 16, 23, 29 (6 and 12 hours after infestation), and 30.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19742443/