Brain ventricle size differences in young and old Bichon dogs

Abstract

Cognitive Dysfunction Syndrome (CDS) is a neurodegenerative condition in dogs, often compared to human Alzheimer's disease due to clinical and morpho-pathological similarities. Diagnosis relies on patient history, owner input, clinical examination, cognitive assessment, and paraclinical investigations like CT scans, which can reveal structural brain changes such as cerebral atrophy and ventricular enlargement. Given the anatomical diversity among breeds, breed-specific studies are necessary. This study evaluates ventricular sizes and the ratio between ventricles and corresponding hemispheres in Bichon dogs, comparing individuals under 9 years of age with those over 9. Results indicate that older dogs exhibit larger ventricular measurements, suggesting age-related ventricular enlargement. These findings contribute to understanding age-associated neurodegenerative changes in this breed.