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Peer-reviewed veterinary case report

Comparative protective efficacy of a newly generated live recombinant thermostable highly attenuated vaccine rK148/GVII-F using a single regimen against lethal NDV GVII.1.1.

Journal:
Avian pathology : journal of the W.V.P.A
Year:
2024
Authors:
Abdallah Mouhamed, Amal et al.
Affiliation:
Department of Avian Diseases

Abstract

A thermostable, safe, and effective NDV GVII recombinant vaccine was generated.Fusion gene replacement with GVII did not affect GI K148/08 virus thermostability.Strain rK148/GVII-F provided adequate protection against a lethal NDV challenge.Oropharyngeal shedding was significantly reduced on post-challenge days 5 and 7.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38009206/