Peer-reviewed veterinary case report
Comparative study of oral versus subcutaneous B:9-23 insulin peptide in Balb/c mice as an experimental model for autoimmune diabetes.
- Journal:
- Annals of the New York Academy of Sciences
- Year:
- 2004
- Authors:
- Devendra, Devasenan et al.
- Affiliation:
- University of Colorado Health Sciences Center · United States
- Species:
- rodent
Abstract
Insulin peptide B:9-23 (amino acids 9 to 23 of the B chain) can induce immune targeting of insulin and islets in normal Balb/c mice. The insulin autoantibodies induced react with insulin and not the immunizing peptide. Oral administration of insulin as well as subcutaneous insulin can sensitize to insulin.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15681773/