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Peer-reviewed veterinary case report

Balloon treatment for pulmonary valve narrowing in children and dogs

By Markovic, L E et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2025·Department of Small Animal Medicine and Surgery, United States·View original on PubMed

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Original publication title: Comparative transcatheter intervention for pulmonary valve stenosis: multicenter collaborative study across pediatric and veterinary cardiology centers.

Species:
dog
Breathing & coughDogs

Plain-English summary

A group of 165 dogs with pulmonary valve stenosis (a heart condition) underwent a procedure called balloon pulmonary valvuloplasty to help improve their heart function. The study found that 84% of these dogs had successful outcomes, meaning their heart pressure improved significantly after the procedure. Many of the dogs were also given beta-blockers to help manage their condition. Overall, the treatment was effective, and most dogs showed improvement in their heart health after the intervention.

People also search for: dog heart problems treatment · balloon valvuloplasty for dogs · pulmonary valve stenosis in dogs

Abstract

INTRODUCTION/OBJECTIVES: Transcatheter therapeutics have revolutionized treatment of pulmonary valve stenosis (PS). Further understanding of PS intervention may help improve outcomes for different species. This study describes characteristics and immediate outcomes in children and dogs undergoing balloon pulmonary valvuloplasty (BPV) or transpulmonary stent implantation for congenital PS. ANIMALS, MATERIALS, AND METHODS: This is a multicenter, retrospective review from two pediatric and three veterinary centers. Demographics, procedural characteristics, and outcomes were assessed. Successful intervention was defined as a 50%&#xa0;reduction in transvalvar pulmonary pressure gradient (PG) within 24&#xa0;h or final invasive transpulmonary gradient <40&#xa0;mmHg. RESULTS: Data (78 children; 165 dogs) from July 2019 to June 2021 were included, with BPV performed in 77 children and 145 dogs and stent implantation in one child and 20 dogs. Stenosis was valvar in 64 children (82%) and 141 dogs (86%; P=0.50). Mean (SD) initial echocardiographic peak PG was higher in dogs [122&#xa0;mmHg (39 mmHg) vs. 70&#xa0;mmHg (22 mmHg)]. More dogs received beta-blockade at intervention (92% vs. 3%). Congestive heart failure was evident in 14% of dogs but no children. Pulmonary valve annulus diameter and balloon-to-annulus ratio were smaller in children [8.7&#xa0;mm (3.4&#xa0;mm); 1.19 (0.3&#xa0;mm)] vs. dogs [12.6&#xa0;mm (4.2&#xa0;mm); 1.28 (0.24&#xa0;mm)]. Successful transcatheter intervention was achieved in 84% of dogs and 96% of children (P=0.008). CONCLUSIONS: Valvar PS occurs in both children and dogs, although lesions might not be completely comparable. Preprocedural PG is higher, and beta-blockers are more commonly prescribed in dogs. Successful transpulmonary intervention can be achieved in most pediatric and canine patients.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39914359/