Peer-reviewed veterinary case report
Puppy immune response to two commercial parvo, distemper
By Bergman, J G H E et al.·Published in The Veterinary record·2006·Intervet UK, United Kingdom·View original on PubMed →
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Original publication title: Comparative trial of the canine parvovirus, canine distemper virus and canine adenovirus type 2 fractions of two commercially available modified live vaccines.
- Species:
- dog
Plain-English summary
A group of puppies was vaccinated with two different commercial vaccines to protect against canine parvovirus, canine distemper virus, and canine adenovirus type 2. The puppies were given their first vaccination at six weeks and a second one at ten weeks. After the first vaccination, most puppies showed a good immune response, and those that didn't respond initially were able to develop immunity by the second vaccination. This means that both vaccines were effective in helping the puppies build protection against these serious diseases.
People also search for: puppy vaccination schedule · canine parvovirus vaccine effectiveness · puppy distemper vaccine response
Abstract
The results of vaccinating two groups of puppies with commercial vaccines, both of which claimed to provide adequate protection with a final vaccination at 10 weeks of age, were compared. Groups of 19 and 20 puppies with similar titres of maternally derived antibodies against canine parvovirus (cpv), canine distemper virus (cdv) and canine adenovirus type 2 (cav-2) at four weeks of age were vaccinated at six and 10 weeks of age and their responses to each vaccination were measured by comparing the titres against cpv, cdv and cav-2 in the serum samples taken immediately before the vaccination and four weeks later. After the vaccination at six weeks of age, all 19 of the puppies in group 1 had responded to cpv and cdv, and 14 had responded to cav-2; in group 2, 17 of the 20 had responded to cpv, 19 to cdv and 15 to cav-2. In both groups the puppies that did not respond to the first vaccination had responded serologically to cpv, cdv and cav-2 at 10 weeks of age.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17127756/