Peer-reviewed veterinary case report
Comparing skin test and blood test for dog atopic dermatitis diagnosis
By Tarpataki, N et al.·Published in Schweizer Archiv fur Tierheilkunde·2008·Department and Clinic of Internal Medicine·View original on PubMed →
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Original publication title: Comparison between an intradermal skin test and allergen-specific IgE-ELISA for canine atopic dermatitis.
- Species:
- dog
Plain-English summary
A group of 210 dogs with atopic dermatitis (a skin allergy) underwent two tests to identify what was causing their symptoms. The first test was an intradermal skin test, and the second was a blood test that measures specific IgE antibodies. Both tests identified common allergens like dust mites and certain plants. The blood test was found to be quite accurate, with a sensitivity of 82.4% and specificity of 93.8%, making it a reliable option for diagnosing allergies in dogs. This information can help veterinarians create effective treatment plans, including immunotherapy.
People also search for: dog skin allergy test · atopic dermatitis treatment for dogs · dog allergy blood test
Abstract
The aim of this study was to compare the results of an intradermal skin test (IDST) with those of an allergen-specific IgE-ELISA in 210 dogs with atopic dermatitis. All the dogs had a clinical diagnosis of atopic dermatitis and underwent an IDST. The sera of all dogs were analysed for allergen-specific IgE by ELISA using the monoclonal antibody D9 against dog IgE. IDST was used as the standard assay. In both methods, the following antigens provided a positive test result: Dermatophagoides farinae, Acarus siro, Tyrophagus putrescentiae, ragweed, mugwort and Lepidoglyphus destructor. ELISA had an overall sensitivity of 82.4% and an overall specificity of 93.8%. The overall accuracy of the ELISA was 91.3%. The evaluated monoclonal D9 ELISA was found to be a reliable tool for the diagnosis of those allergens that cause clinical atopy, and can be recommended for use in dogs when immunotherapy is a therapeutic option.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18429502/