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Peer-reviewed veterinary case report

Immunity in adult dogs after two types of multivalent vaccines

By Cunha, Rafes D S et al.·Published in Veterinary medicine and science·2020·Centro Universit&#xe1·View original on PubMed

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Original publication title: Comparison of immunity against canine distemper, adenovirus and parvovirus after vaccination with two multivalent canine vaccines.

Species:
dog

Plain-English summary

A study involving 60 adult dogs in Brazil compared two different vaccines to see how well they protected against serious viral diseases like canine distemper, parvovirus, and adenovirus. One group received a local vaccine called Elevencell, while the other group got an imported vaccine from the U.S. Both vaccines showed similar effectiveness, with the Elevencell vaccine providing strong protection in most dogs. This suggests that the local vaccine is just as good as the imported one for keeping dogs safe from these dangerous viruses.

People also search for: dog vaccines effectiveness · canine distemper vaccine · parvovirus vaccine for dogs · Elevencell vaccine review

Abstract

BACKGROUND: Viral diseases are a major cause of morbidity and mortality in puppies. There is a belief among veterinary practitioners and even educational institutions that the vaccines made in Brazil against canine distemper virus (CDV), canine parvovirus (CPV) and canine adenovirus (CAV) are ineffective or only partially effective. OBJECTIVES: This study aimed at comparing the immunity of two multivalent vaccines in adult dogs in the city of Uberlândia, Minas Gerais state, Brazil. METHODS: The study was carried out at the Animal Protection Association and a total of 60 adult mongrel dogs were selected and divided into two groups. Group A was immunized with two doses of Elevencellvaccine and Group B received two doses of imported vaccine from the United States; each group was made up of 14 females and 14 males. RESULTS: In group A, the Elevencell vaccine generated a protective antibody titre against CDV in 26 out of 28 subjects (92.85%), CPV in 24 out of 28 subjects (85.71%) and CAV in 26 out of 28 subjects (92.85%). In group B, the imported US vaccine generated a protective antibody titre against CDV in 22 out of 28 subjects (78.57), CPV in 21 out of 28 subjects (75%) and CAV in 25 out of 28 subjects (89.28%). There was no statistical difference between titres generated between vaccine types for any of the three diseases tested. CONCLUSION: Elevencell vaccine titres were not inferior to the imported US vaccine in conferring protective titres against CDV, CPV and CAH, which confirms the efficacy of this product.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32338828/