Peer-reviewed veterinary case report
Does corticosteroid treatment help dogs with acute pancreatitis
By Okanishi, H et al.·Published in The Journal of small animal practice·2019·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Comparison of initial treatment with and without corticosteroids for suspected acute pancreatitis in dogs.
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with acute pancreatitis received treatment either with a corticosteroid called prednisolone or without it. The dogs treated with prednisolone showed quicker improvement in their symptoms and had lower levels of a specific protein linked to inflammation. Additionally, these dogs had a significantly lower chance of dying within a month after leaving the hospital compared to those who did not receive the steroid. Overall, using prednisolone helped these dogs recover faster and more safely from their condition.
People also search for: dog pancreatitis treatment · prednisolone for dogs · signs of pancreatitis in dogs
Abstract
OBJECTIVES: To compare initial treatment with and without corticosteroids for acute pancreatitis in dogs and investigate the therapeutic efficacy and prognosis. MATERIALS AND METHODS: Sixty-five dogs were included in this non-blinded, non-randomised clinical study. Dogs with acute pancreatitis received treatment either with dose of 1 mg/kg/day prednisolone (n=45) or without prednisolone (n=20). Response to treatment was based on changes in the C-reactive protein concentration, improvement in clinical signs, duration of hospitalisation, mortality and recurrence rate. RESULTS: From the third day of hospitalisation, C-reactive protein concentration was significantly lower in the prednisolone group than that in the non-prednisolone group. The number of days required to reach a C-reactive protein concentration of <2 mg/dL and clinical score of ≤2 was significantly lower in the prednisolone group. The mortality rate 1 month after discharge was significantly lower in the prednisolone group (11.3% versus 46.1%). CLINICAL SIGNIFICANCE: In dogs with acute pancreatitis, initial treatment with prednisolone resulted in earlier reductions in C-reactive protein concentration and earlier improvement of clinical signs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30868606/