Peer-reviewed veterinary case report
Platelet count methods compared in Cavalier King Charles Spaniels
By Olsen, Lisbeth H et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2004·Department of Anatomy and Physiology·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Comparison of manual and automated methods for determining platelet counts in dogs with macrothrombocytopenia.
- Species:
- dog
Plain-English summary
A group of Cavalier King Charles Spaniels with low platelet counts (macrothrombocytopenia) were tested to see how different methods of counting platelets compared. The study found that while all methods showed good agreement, manual counting methods were the most accurate. The dogs with lower platelet counts had larger platelets compared to healthy dogs. This information can help veterinarians choose the best method for diagnosing and monitoring dogs with this condition.
People also search for: Cavalier King Charles Spaniel low platelet count · macrothrombocytopenia in dogs · dog platelet count testing methods
Abstract
Platelet counts were performed in 43 Cavalier King Charles Spaniels (CKCS, a breed predisposed to macrothrombocytopenia) and in 10 control dogs using 3 automated systems and 3 manual methods (erythrocyte-lysing agents + counting chamber or evaluation of blood smear). Good correlations were found between platelet counts using all methods (all P < 0.0001; R2 = 0.71-0.85). Best correlations were found between the manual methods. Significantly larger platelets were found in CKCS with platelet count < or = 100,000/microl when compared with control dogs and CKCS with platelet count > 100,000/microl (both P < 0.0001). All platelet counts--except when made with the 2 counting chamber methods--were underestimated at platelet counts < or = 100,000/microl.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15053372/