Peer-reviewed veterinary case report
Interleukin 10 levels in dogs with first time and recurring Demodex
By Felix, A O C et al.·Published in Veterinary parasitology·2013·Faculdade de Veteriná, Brazil·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Comparison of systemic interleukin 10 concentrations in healthy dogs and those suffering from recurring and first time Demodex canis infestations.
- Species:
- dog
Plain-English summary
A group of dogs with skin problems caused by a mite called Demodex canis were tested for a specific immune marker (interleukin 10) to see how it compared to healthy dogs. The study found that dogs with recurring cases of Demodex had much higher levels of this marker than both healthy dogs and those experiencing the condition for the first time. This suggests that dogs with ongoing issues may have a different immune response. If your dog has skin issues that keep coming back, it might be worth discussing these findings with your veterinarian.
People also search for: dog skin problems Demodex · why does my dog keep getting skin infections · treatment for recurring dog skin issues
Abstract
OBJECTIVE: The objective of this study was to assess the interleukin 10 (IL-10) concentrations in the sera of dogs suffering from demodicosis. METHODS: Twenty-six dogs were distributed into three groups: demodicosis groups G1, n=11 (recurring disease) and G2, n=6 (first time occurrence), and a control group, G3, n=9 (healthy dogs). All the animals were subjected to skin scrape tests and blood harvesting for serum extraction. In G1 and G2 only those animals with Demodex canis positive skin tests were included, while healthy dogs were included in G3. To assess IL-10 levels the commercial Quantikine Canine IL-10 Immunoassay(®) (R&D Systems) kit was used. RESULTS: The mean IL-10 level obtained for G1 was 269.4 pg/ml (sd=290.8 pg/ml), for G2 it was 28.5 pg/ml (sd=19.7 pg/ml) while the mean for G3 was 11.9 pg/ml (sd=2.3 pg/ml). There was a significant difference between G1 and the other two groups. CONCLUSIONS: According to our results, dogs with reoccurring demodicosis have higher IL-10 levels than healthy dogs and those suffering the disease for the first time.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23218225/