Peer-reviewed veterinary case report
Treating no heat in female dogs with cabergoline or gonadotrophin
By Nak, D et al.·Published in Australian veterinary journal·2012·Department of Obstetrics and Gynaecology·View original on PubMed →
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Original publication title: Comparison of the use of cabergoline and gonadotrophin to treat primary and secondary anoestrus in bitches.
- Species:
- horse
Plain-English summary
A group of 39 healthy female dogs, aged 2 to 6 years, were treated for a lack of heat cycles (known as anoestrus) using either cabergoline or pregnant mare's serum gonadotrophin (PMSG). Both treatments successfully induced heat in the dogs, but cabergoline proved to be more effective for achieving pregnancy and successful whelping compared to PMSG. This means that if your dog is not going into heat, cabergoline may be a better option to help her become fertile again.
People also search for: why is my dog not going into heat · cabergoline for dogs · treating anoestrus in bitches
Abstract
OBJECTIVE:   To determine the efficacy and reliability of cabergoline and pregnant mare's serum gonadotrophin (PMSG) for induction of oestrus in bitches with primary or secondary anoestrus. PROCEDURES:   We studied 39 healthy bitches of various breeds aged 2-6 years and in primary or secondary anoestrus: 20 bitches were administered 5 µg/kg/day cabergoline orally until day 2 after the onset of pro-oestrus or for a maximum of 42 days, and 19 bitches were administered 20 IU/kg/day PMSG intramuscularly for 5 consecutive days, followed by an additional single injection of 25 IU/kg of human chorionic gonadotrophin on the fifth day. RESULTS:   The rates of oestrus induction in the primary and secondary anoestrous bitches treated with cabergoline and PMSG were found to be similar. Pregnancy and whelping rates in the cabergoline group were statistically different from the rates in the PMSG group (P < 0.001). CONCLUSION:   Cabergoline is more effective and reliable for the induction of a fertile oestrus in bitches with primary or secondary anoestrous.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22510079/