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Peer-reviewed veterinary case report

Comparison of three DNA extraction methods for molecular confirmation of Mycobacterium avium subspecies paratuberculosis from the VersaTrek™ liquid cultures of bovine fecal samples.

Journal:
Journal of microbiological methods
Year:
2018
Authors:
Thirumalapura, Nagaraja R et al.
Affiliation:
Pennsylvania Department of Agriculture · United States

Abstract

We evaluated three DNA extraction methods for confirmation of Mycobacterium avium subspecies paratuberculosis from liquid cultures of bovine feces. Use of DNA Extract All Reagents Kit™ resulted in efficient extraction of amplifiable DNA from higher proportion (96.29%) of known positive samples compared to Chelex-100 resin (25.92%) and polyethylene glycol (0%).

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30031737/