Peer-reviewed veterinary case report
Comparing two liver biopsy methods in dogs with liver disease
By Fernandez, N et al.·Published in The Journal of small animal practice·2017·Royal (Dick) School of Veterinary Studies, United Kingdom·View original on PubMed →
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Original publication title: Comparison of two minimally invasive techniques for liver biopsy collection in dogs.
- Species:
- dog
Plain-English summary
Fifteen dogs with suspected liver disease underwent laparoscopic liver biopsies using two different techniques: a pre-tied ligating loop and cup biopsy forceps. The biopsies taken with the ligating loop were larger and contained more useful tissue, but it took longer to perform compared to the cup forceps method. Both techniques were effective, but the ligating loop provided better quality samples for diagnosing liver issues. This suggests that while it may take more time, the pre-tied ligating loop could be a better choice for obtaining liver biopsies in dogs.
People also search for: dog liver disease biopsy · laparoscopic liver biopsy for dogs · liver biopsy techniques in dogs
Abstract
OBJECTIVES: High-quality biopsy is an essential factor for the successful diagnosis of canine liver disease. The aim of this study was to compare various aspects of biopsies obtained by two different techniques: pretied ligating loop and cup biopsy forceps. MATERIALS AND METHODS: Fifteen client-owned dogs underwent laparoscopic liver biopsies for diagnosis of liver disease. Biopsies were obtained from the same liver lobe using a pre-tied ligating loop and cup biopsy forceps. Biopsy weight, volume, histological value and surgical time were compared between the two techniques. Surgical complications were recorded. RESULTS: Samples obtained with the pre-tied ligating loop were significantly heavier and larger in volume than those obtained with cup biopsy forceps. Samples obtained with the ligating loop contained significantly more portal tracts and less crush and fragmentation artefacts. The time required to obtain a liver biopsy with the pre-tied ligating loop was approximately double that of the cup biopsy forceps technique. CLINICAL SIGNIFICANCE: The use of a pre-tied ligating loop is a good alternative to the cup biopsy forceps technique when acquiring laparoscopic liver biopsies in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28737268/