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Peer-reviewed veterinary case report

Comparison of two prevalent individually ventilated caging systems for detection of murine infectious agents via exhaust air particles.

Journal:
Laboratory animals
Year:
2019
Authors:
Mahabir, Esther et al.
Affiliation:
University of Cologne · Germany
Species:
rodent

Abstract

We compared the efficacies of two different individually ventilated cage systems (Allentown and Tecniplast) for health monitoring (HM) of murine infectious agents using exhaust air particle (EAP) capture and real-time PCR. After three months of monitoring, both EAP capture media allowed detection of Helicobacter, Pasteurella and Entamoeba. Use of the EAP real-time PCR for HM reduces the number of mice used.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30012043/