Peer-reviewed veterinary case report
Comparison of two shampoos to treat yeast skin infection in dogs
By Maynard, L et al.·Published in The Journal of small animal practice·2011·VIRBAC SA, France·View original on PubMed →
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Original publication title: Comparison of two shampoos for the treatment of canine Malassezia dermatitis: a randomised controlled trial.
- Species:
- dog
Plain-English summary
A group of 67 dogs with skin issues caused by a yeast overgrowth (Malassezia dermatitis) were treated with either a chlorhexidine shampoo or a combination shampoo containing miconazole and chlorhexidine. Both shampoos significantly reduced the yeast counts and improved skin conditions like itching, redness, and scaling over six weeks. There was no major difference in effectiveness between the two shampoos, and both worked well to clear up the skin problems. A few dogs had minor side effects from the chlorhexidine shampoo, but overall, both treatments were effective.
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Abstract
OBJECTIVES: Two antimicrobial shampoos for treatment of canine Malassezia dermatitis (CMD) were compared in a prospective, randomised, single-blinded, field clinical trial. METHODS: Sixty-seven dogs with pedal or generalised dermatitis associated with Malassezia overgrowth (MO) were treated with 3% chlorhexidine shampoo (3%CHX) or 2% miconazole-2% chlorhexidine shampoo (2%MIC/CHX) and evaluated for up to 6 weeks until cytological recovery. Pruritus, erythema, papules, greasy seborrhoea, scaling, malodour, excoriations, secondary hairloss, lichenification, hyperpigmentation and lesion extent were each scored on a 0-3 severity scale and combined making an aggregate score. RESULTS: Among 54 dogs with good treatment compliance, reduction of yeast counts by at least 88% was recorded in 21 of 22 dogs with 3%CHX and 30 of 32 dogs with 2%MIC/CHX. No significant difference was detected between products for yeast count reduction (P=0·592). Time to cytological recovery was not significantly different between groups (P=0·960). Lesion score was significantly reduced in both groups after treatment (72·5 ±25·7% with 3%CHX versus 78·7 ±22·3% with 2%MIC/CHX, P=0·309). Four dogs treated with chlorhexidine shampoo showed minor adverse effects. CLINICAL SIGNIFICANCE: In this study, 3%CHX was clinically as effective as 2%MIC/CHX for treatment of CMD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21985533/