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Peer-reviewed veterinary case report

Complete genome sequence of a J subgroup avian leukosis virus isolated from local commercial broilers.

Journal:
Journal of virology
Year:
2012
Authors:
Li, Hongxin et al.
Affiliation:
College of Animal Science · China
Species:
bird

Abstract

Subgroup J avian leukosis virus (ALV-J) isolate GDKP1202 was isolated from a 50-day-old local yellow commercial broiler in the Guangdong province of China in 2012. Here we report the complete genomic sequence of the GDKP1202 isolate, which caused high mortality, serious growth suppression, thymic atrophy, and liver enlargement in commercial broilers. A novel potential binding site (5'-GGCACCTCC-3') for c-myb was identified in the GDKP1202 genome. These findings will provide additional insights into the molecular characteristics in the genomes and pathogenicity of ALV-J.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23043170/