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Peer-reviewed veterinary case report

Complete genome sequence of a mammalian species-infectious and -pathogenic H6N5 avian influenza virus without evidence of adaptation.

Journal:
Journal of virology
Year:
2012
Authors:
Park, Seong-Jun et al.
Affiliation:
Korea Research Institute of Bioscience and Biotechnology · South Korea
Species:
bird

Abstract

An H6N5 avian influenza virus (AIV) strain, designated A/aquatic bird/Korea/CN5/2009 (H6N5), was isolated from fecal swabs of aquatic birds in 2009, and surprisingly, it showed infectivity and pathogenicity in mammalian species without evidence of adaptation. In this study, we report the first complete genome sequence containing 3' and 5' noncoding regions (NCRs) of a mammalian species-infectious and pathogenic H6N5 AIV, which will help provide important insights into the molecular basis of pathogenesis, transmission, and evolution of AIV.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23087119/