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Peer-reviewed veterinary case report

Complete Sequences of IncU Plasmids Harboring Quinolone Resistance Genes qnrS2 and aac(6')-Ib-cr in Aeromonas spp. from Ornamental Fish.

Journal:
Antimicrobial agents and chemotherapy
Year:
2016
Authors:
Dobiasova, Hana et al.
Affiliation:
Department of Biology and Wildlife Diseases

Abstract

The nucleotide sequences of three IncU plasmids from Aeromonas spp. isolated from ornamental fish are described. They had a typical IncU backbone for plasmid replication and maintenance functions, but conjugative transfer modules were disrupted. The gene qnrS2 was inserted into mpR as a mobile insertion cassette. Novel Tn3 family transposons carrying putative toxin-antitoxin and plasmid stability genes were identified. The study demonstrates high plasticity of IncU plasmids from aquatic environments.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/26525788/