Peer-reviewed veterinary case report
Complications in dogs after high-dose prednisolone for nerve injury
By Culbert, L A et al.·Published in Journal of the American Animal Hospital Association·1998·Department of Surgery, United States·View original on PubMed →
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Original publication title: Complications associated with high-dose prednisolone sodium succinate therapy in dogs with neurological injury.
- Species:
- dog
Plain-English summary
A group of 105 dogs with neurological injuries received high doses of a corticosteroid called prednisolone to help with their condition. While most dogs improved, about one-third experienced side effects like diarrhea, vomiting, and loss of appetite. Fortunately, these complications were generally mild and resolved on their own after stopping the medication, without needing extra treatment or causing longer hospital stays.
People also search for: dog neurological injury treatment · side effects of prednisolone in dogs · dog vomiting after medication
Abstract
A retrospective study of 105 dogs with neurological injury was conducted to evaluate the type and prevalence of complications encountered when treatment consisted of a high-dose corticosteroid protocol. All dogs were treated with high-dose prednisolone sodium succinate (HDPSS) (30 mg/kg body weight, administered intravenously [i.v.] q 6 hrs for 36 hrs). Thirty-five (33.3%) cases developed complications including diarrhea (n = 11), melena (n = 11), vomiting (n = 6), hematochezia (n = 3), hematemesis (n = 1), anorexia (n = 1), or a combination (n = 2). Most complications resolved without additional treatments after termination of the HDPSS therapy. None of the complications were considered serious, and none prolonged hospitalization.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9507425/