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Peer-reviewed veterinary case report

Complications of liver disease in dogs and cats

By Lidbury, Jonathan A·Published in The Veterinary clinics of North America. Small animal practice·2025·Department of Veterinary Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Complications of Liver Disease.

Plain-English summary

A dog with liver disease may experience vomiting and other complications. To help manage these symptoms, veterinarians often use anti-nausea medications and recommend a special diet low in sodium. If the dog develops fluid buildup in the abdomen (ascites), treatments like spironolactone and furosemide can help. Additionally, if the dog shows signs of confusion or disorientation (hepatic encephalopathy), a diet change and medications like lactulose may be necessary. It's important for pet owners to monitor their dog's condition closely, as liver disease can lead to serious issues with bleeding or clotting.

People also search for: dog vomiting liver disease treatment · dog ascites management · hepatic encephalopathy in dogs treatment

Abstract

Hepatobiliary disease in dogs and cats can lead to various complications. Vomiting is a common clinical sign in liver disease, and antiemetic therapy should be considered on a case-by-case basis. Ascites is managed by feeding a moderate sodium diet, therapy with spironolactone, and judicious use of furosemide. Hepatic encephalopathy is managed by feeding an appropriate diet and treating with lactulose and possibly an antimicrobial. Because coagulant and anticoagulant factors are affected in patients with hepatic dysfunction, they may be in an altered but balanced hemostatic state. This balance is fragile and bleeding or thrombosis can occur if it is disrupted.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40379581/