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Peer-reviewed veterinary case report

Computed Tomography of Lobular Dissecting Hepatitis in a Young Golden Retriever.

Journal:
Journal of the American Animal Hospital Association
Year:
2019
Authors:
Hostnik, Eric T et al.
Affiliation:
From the Department of Veterinary Clinical Sciences · United States
Species:
dog

Abstract

A 9 mo old female intact golden retriever presented for evaluation of chronic lethargy and decreased appetite. The serum biochemistry profile revealed increased liver enzymes consistent with a mixed hepatocellular and cholestatic pattern. A multiphase computed tomography angiography was performed to evaluate for a portosystemic shunt. Numerous hyperattenuating nodules were identified throughout the liver on the noncontrast-enhanced series. Histologic evaluation of percutaneous needle biopsy samples of a liver nodule showed a rare form of hepatitis called lobular dissecting hepatitis. Lobular dissecting hepatitis should be considered as a differential in young dogs with precontrast hyperattenuating hepatic nodules on noncontrast-enhanced computed tomography.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30653361/