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Peer-reviewed veterinary case report

CT scan shows rare liver hepatitis in young Golden Retriever

By Hostnik, Eric T et al.·Published in Journal of the American Animal Hospital Association·2019·From the Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Computed Tomography of Lobular Dissecting Hepatitis in a Young Golden Retriever.

Species:
dog
Stomach & digestionDogs

Plain-English summary

A 9-month-old female Golden Retriever was brought to the vet because she was very tired and not eating well. Blood tests showed that her liver enzymes were higher than normal, which can indicate liver problems. A special scan of her liver revealed several unusual nodules, and a biopsy confirmed she had a rare type of liver inflammation called lobular dissecting hepatitis. This condition can occur in young dogs and requires careful monitoring and treatment.

People also search for: puppy lethargy and loss of appetite · Golden Retriever liver disease · lobular dissecting hepatitis in dogs

Abstract

A 9 mo old female intact golden retriever presented for evaluation of chronic lethargy and decreased appetite. The serum biochemistry profile revealed increased liver enzymes consistent with a mixed hepatocellular and cholestatic pattern. A multiphase computed tomography angiography was performed to evaluate for a portosystemic shunt. Numerous hyperattenuating nodules were identified throughout the liver on the noncontrast-enhanced series. Histologic evaluation of percutaneous needle biopsy samples of a liver nodule showed a rare form of hepatitis called lobular dissecting hepatitis. Lobular dissecting hepatitis should be considered as a differential in young dogs with precontrast hyperattenuating hepatic nodules on noncontrast-enhanced computed tomography.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30653361/