Peer-reviewed veterinary case report
Dogs with Cushing's disease often also have diabetes mellitus
By Miceli, D D et al.·Published in Research in veterinary science·2017·os Animales y Hospital Escuela de Medicina Veterinaria·View original on PubMed →
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Original publication title: Concurrent hyperadrenocorticism and diabetes mellitus in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with hyperadrenocorticism (HAC), a condition that causes excessive hormone production, were found to also have diabetes mellitus (DM) in about 14% of cases. This combination can lead to more serious health issues and a shorter lifespan for affected dogs. Factors like high blood sugar levels, certain body conditions, and being a non-castrated female dog increased the risk of developing diabetes alongside HAC. Managing both conditions is crucial for improving the health and longevity of these dogs.
People also search for: dog diabetes treatment · hyperadrenocorticism in dogs · symptoms of diabetes in dogs · dog hormone imbalance · managing diabetes and Cushing's disease in dogs
Abstract
Hyperadrenocorticism (HAC) and diabetes mellitus (DM) are two diseases that can occur concurrently in dogs. The objective of this study was to evaluate the coexistence of HAC and DM, and the risk factors involved that could contribute to the development of DM in dogs with HAC. A total of 235 dogs with HAC were studied and, according to their fasting glycemia, they were divided into three groups: <5.6mmol/L, between 5.6 and 10.08mmol/L and >10.08mmol/L. The following parameters were evaluated: age, gender, cause of HAC, body condition, glycemia, total cholesterol, triglycerides, urinary cortisol:creatinin ratio (UCCR) and survival time. A 13.61% concurrence of HAC and DM was observed. Dogs with a fasting glycemia >5.6mmol/L, with dislipemia, with Pituitary-Dependent Hyperadrenocorticism, UCCR >100×10and non-castrated females showed a higher risk of developing DM. The development of DM in dogs with HAC reduces the survival time.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28759861/