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Peer-reviewed veterinary case report

Dog with lymphangioma, low platelets, and von Willebrand's disease

By Woods, J P et al.·Published in Journal of the American Animal Hospital Association·1995·Department of Clinical Studies, Canada·View original on PubMed

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Original publication title: Concurrent lymphangioma, immune-mediated thrombocytopenia, and von Willebrand's disease in a dog.

Species:
dog

Plain-English summary

A 14-month-old female dachshund was brought in with swelling around her mouth and bleeding problems. Tests showed she had low platelet counts and issues related to blood clotting, which indicated immune-mediated thrombocytopenia (a condition where the immune system attacks platelets) and von Willebrand's disease (a bleeding disorder). The vet treated her successfully with glucocorticoid medication, which helped resolve the immune issue. Unfortunately, the lymphangioma (a type of benign tumor) was too large to remove surgically, but the dog is managing her conditions with ongoing care.

People also search for: dachshund bleeding problems · dog immune-mediated thrombocytopenia treatment · von Willebrand's disease in dogs

Abstract

Lymphangioma, immune-mediated thrombocytopenia (IMT), and von Willebrand's disease (vWD) were diagnosed by histology, hematology, and a coagulation profile in a 14-month-old, female dachshund. Clinical and laboratory findings included ecchymotic inguinolabial swelling, thrombocytopenia, positive platelet factor-3 assay, prolonged buccal mucosal bleeding time, and subnormal von Willebrand factor antigen concentration and factor VIII activity. The IMT resolved with immunosuppressive glucocorticoid therapy. Histologic examination identified lymphangioma which was too extensive for surgical excision. The history and the clinical and laboratory findings were consistent with congenital vWD, although acquired vWD secondary to lymphangioma could not be ruled out.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7820768/