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Peer-reviewed veterinary case report

Conduction block of peripheral nerve using high-frequency alternating currents delivered through an intrafascicular electrode.

Journal:
Muscle & nerve
Year:
2010
Authors:
Ackermann, D Michael et al.
Affiliation:
Case Western Reserve University · United States

Abstract

Many diseases are characterized by undesired or pathological neural activity. The local delivery of high-frequency currents has been shown to be an effective method for blocking neural conduction in peripheral nerves and may provide a therapy for these conditions. To date, all studies of high-frequency conduction block have utilized extraneural (cuff) electrodes to achieve conduction block. In this study we show that high-frequency conduction block is feasible using intrafascicular electrodes.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19813186/