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Peer-reviewed veterinary case report

Bleeding after surgery in a young female cat due to factor XI

By Troxel, Mark T et al.·Published in Journal of the American Animal Hospital Association·2002·Garden State Veterinary Specialists, United States·View original on PubMed

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Original publication title: Congenital factor XI deficiency in a domestic shorthair cat.

Species:
cat

Plain-English summary

A 6-month-old female domestic shorthair cat was brought to the vet after surgery for spaying and declawing because she was bleeding from her paws. Tests showed that her blood took longer than normal to clot due to a deficiency in a specific blood factor called factor XI. Unlike a previous case where the deficiency was caused by inhibitors, this cat's condition was determined to be congenital, meaning she was born with it. The vet confirmed that she did not have any other underlying diseases contributing to the bleeding.

People also search for: cat bleeding from paws · factor XI deficiency in cats · cat surgery bleeding issues

Abstract

A 6-month-old, female, domestic shorthair cat was examined after onychectomy and ovariohysterectomy because of bleeding from the paws. Prolonged activated partial thromboplastin time was discovered, Coagulation factor analyses revealed deficiency of factor XI coagulant activity. Plasma mixing studies indicated factor deficiency or dysfunction rather than factor inhibition. Feline factor XI deficiency in one adult cat has been previously reported but was attributed to factor XI inhibitors. The signalment, lack of primary disease, and the finding of persistent factor XI deficiency in the absence of coagulation inhibitors were considered compatible with congenital factor XI deficiency in the cat of this report.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12428887/