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Peer-reviewed veterinary case report

Vomiting and jaundice in young beagle from liver blood vessel defect

By Yoshizawa, K et al.·Published in Toxicologic pathology·1997·Department of Pathology and General Toxicology, Japan·View original on PubMed

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Original publication title: Congenital intrahepatic arteriovenous fistulae in a young beagle dog.

Species:
dog

Plain-English summary

An 8-month-old female beagle was brought to the vet with symptoms like not eating, vomiting, diarrhea with blood, and yellowing of the skin (jaundice) for about two weeks. Blood tests showed high levels of liver enzymes and other indicators of liver distress. The vet found that the dog's liver was severely atrophied and had abnormal blood vessels. Unfortunately, due to the severity of the liver condition, treatment options were limited, and the prognosis was poor.

People also search for: beagle vomiting and diarrhea · jaundice in dogs · liver disease in puppies · dog anorexia treatment

Abstract

Congenital intrahepatic arteriovenous fistulae, a rare hepatic vascular anomaly, in an 8-mo-old female beagle dog was investigated. The animal showed anorexia, repeated vomiting, hemorrhagic diarrhea, and jaundice for approximately 2 wk. There was mild to severe increase of serum alkaline phosphatase, glutamic-oxalacetic transaminase, glutamic pyruvic transaminase, total cholesterol, total bilirubin, and gamma-glutamyl transpeptidase. Macroscopically, the main abdominal organs showed hemorrhagic edema together with bloody ascites. Other characteristic findings were severe hepatic atrophy (right medial, quadrate, left medial, and lateral lobes) with multiple vascular cysts and compensatory hypertrophy of the other lobes. The cystic vessels seemed to extend from the proper hepatic arteries and their branches but were indistinguishable from the portal vein. Histopathologically, the atrophied hepatic lobes were characterized by wide, fibrous septa containing severe hyperplasia and anastomosis of the arteriolae and venulae and proliferation of bile ducts.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9323840/