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Peer-reviewed veterinary case report

Congenital skin scaling in two Yorkshire terrier puppies

By Lorente-Méndez, C et al.·Published in Veterinary dermatology·2026·LABOKLIN GmbH & Co. KG, Germany·View original on PubMed

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Original publication title: Congenital Non-Epidermolytic Ichthyosis in Two Littermate Mixed-Breed Yorkshire Terriers.

Species:
dog

Plain-English summary

Two mixed-breed Yorkshire terrier puppies were diagnosed with congenital non-epidermolytic ichthyosis, a skin condition that causes dry, scaly skin. A skin biopsy confirmed the diagnosis, but genetic tests did not show any known mutations. The puppies responded well to topical treatments that improved their skin condition, but the symptoms returned when the treatment was stopped. This case highlights that lifelong management is necessary for dogs with this condition to keep their skin healthy.

People also search for: Yorkshire terrier skin problems · puppy ichthyosis treatment · dry skin in dogs

Abstract

Congenital non-epidermolytic ichthyosis was diagnosed in two littermate mixed-breed Yorkshire terrier puppies. Histopathological results confirmed lamellar orthokeratosis; genetic testing for known mutations was negative. Topical treatment improved clinical signs, yet relapse occurred upon discontinuation. This case expands the breeds affected and emphasises the need for life-long management.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41117148/