Peer-reviewed veterinary case report
Danish Swedish Farmdog with congenital Pelger-Huet anomaly blood cells
By Lukaszewska, Janina et al.·Published in Acta veterinaria Scandinavica·2011·Veterinary Health Center·View original on PubMed →
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Original publication title: Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: case report.
- Species:
- dog
Plain-English summary
A 13-year-old Danish/Swedish Farmdog was taken to a vet in Poland for an orthopedic issue. X-rays showed signs of spondylosis and degenerative vertebral disease, which improved with anti-inflammatory medications. A blood test revealed an unusual condition called Pelger-Huët anomaly, where the dog's white blood cells had a specific abnormality. This condition was diagnosed as congenital, meaning the dog was likely born with it. After treatment, the dog's orthopedic problems were managed, but the blood condition persisted without any known cause.
People also search for: Danish/Swedish Farmdog orthopedic problems · Pelger-Huët anomaly in dogs · anti-inflammatory treatment for dog spondylosis
Abstract
A 13 year old Danish/Swedish Farmdog from Denmark was evaluated in a veterinary clinic in Warsaw, Poland for evaluation of an orthopedic problem. Radiographs revealed spondylosis and degenerative vertebral disease, which responded to treatment with anti-inflammatory medications. A predominance of hyposegmented neutrophils and eosinophils containing condensed chromatin and normal cytoplasm were identified on a routine CBC. Follow-up blood film evaluations over the course of 12 months confirmed that the hyposegmented granulocytes persisted. The majority of neutrophils contained Grade 2 nuclei (slightly indented), and the mean nuclear score varied from 1.9 to 2.3. Pelger-Huët anomaly (PHA), presumably congenital, was diagnosed based on persistent hyposegmented granulocytes in the absence of an underlying cause for acquired PHA; genetically related dogs were unavailable for testing to confirm vertical transmission. To the authors' knowledge this is the first report of PHA in a Danish/Swedish Farmdog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21362186/