Peer-reviewed veterinary case report
Congenital Type III von Willebrand's disease unmasked by hypothyroidism in a Shetland sheepdog.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2015
- Authors:
- Scuderi, Margaret et al.
- Affiliation:
- Department of Pathology (Burgess) · Canada
- Species:
- dog
Abstract
A 7-year-old, spayed female Shetland sheepdog had sudden onset of right-sided epistaxis. Diagnostic tests revealed Type III von Willebrand's disease and primary hypothyroidism leading to an acute hypothyroid crisis and acquired factor VIII (FVIII) deficiency. Levothyroxine therapy normalized the serum thyroxine and FVIII concentrations. The delayed onset of disease and the reversible FVIII deficiency that was corrected with levothyroxine therapy, support a role for hypothyroidism in the pathogenesis of this dog's sudden bleeding tendency as has been seen with hypothyroidism in humans.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26347307/