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Peer-reviewed veterinary case report

Do hypoallergenic dog foods cause high fat levels in blood

By Amaral, Andressa Rodrigues et al.·Published in PloS one·2025·Veterinary Teaching Hospital, Brazil·View original on PubMed

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Original publication title: Connection between hypoallergenic food and dyslipidemia in dogs: A nutritional myth?

Species:
dog

Plain-English summary

A group of 35 dogs was fed a commercial hypoallergenic diet for 60 days to see if it caused high levels of fat in the blood, known as dyslipidemia. Despite many veterinarians believing that these diets are too fatty and could lead to health issues, the study found that none of the dogs developed dyslipidemia, and the fat content in hypoallergenic diets was similar to regular maintenance diets. This suggests that hypoallergenic diets are not necessarily harmful in terms of fat content, but more research is needed to understand their long-term effects on dogs, especially those with existing health problems.

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Abstract

The limited education in nutrition contributes to the spread of the "nutritionism" phenomenon, with unfounded concerns about certain diets, such as commercial hypoallergenic ones, and their supposed relationship with the development of dyslipidemia. This study aimed to evaluate the perception of veterinarians on the subject and test its veracity. For this, serum triglyceride and cholesterol data from 35 dogs were analyzed before and after consumption of a commercial hypoallergenic diet for 60 days. In addition, a survey was carried out with veterinarians to assess their beliefs about this diet. Finally, the fat content of commercial maintenance, light and other prescription diets were compared to that of 10 commercial hypoallergenic dog diets. The results showed that most veterinarians believed that hypoallergenic diets could cause dyslipidemia and has too much fat. The analysis showed that hypoallergenic diets have fat content in the range of maintenance diets and majority of prescription diets. Fat content of hypoallergenic diets was only higher than light diets and supporting diets for diabetes available in Brazil. Laboratory analysis identified no dogs with dyslipidemia development during the study. Therefore, hypoallergenic diets do not have a high fat content, but new studies should verify if, when used for prolonged periods, hypoallergenic would lead to dyslipidemia in healthy dogs or dogs with underlying diseases, as well as possible changes in the lipoprotein profile.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40853949/