Peer-reviewed veterinary case report
Felis domesticus papillomavirus 2 found in all cat viral plaques
By Munday, John S & Peters-Kennedy, Jeanine·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2010·Institute of Veterinary·View original on PubMed →
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Original publication title: Consistent detection of Felis domesticus papillomavirus 2 DNA sequences within feline viral plaques.
- Species:
- cat
Plain-English summary
A group of cats with skin lesions known as viral plaques were found to have a specific type of papillomavirus (FdPV-2) present in all samples tested. These plaques can sometimes develop into more serious skin conditions, but the study showed that FdPV-2 is likely the cause of these plaques. The researchers used a special test to confirm the presence of the virus in the plaques, indicating that it plays a role in their formation. This information could help veterinarians better understand and treat skin issues related to papillomavirus in cats.
People also search for: cat skin lesions treatment · feline viral plaques · papillomavirus in cats
Abstract
Viral plaques are well recognized skin lesions of cats. They are thought to be caused by papillomavirus infection; however, the causative papillomavirus is uncertain. In the current study, polymerase chain reaction using 2 consensus primer sets and 1 primer set specific for Felis domesticus papillomavirus 2 (FdPV-2) was used to amplify DNA from a series of 14 feline viral plaques. The FdPV-2 sequences were detected in all 14 viral plaques by the specific primers but in only 1 of 14 feline cutaneous trichoblastomas. Papillomavirus DNA was amplified from 8 plaques using the consensus primers. Sequences from FdPV-2 were amplified using the consensus primers from 4 plaques. In addition, 3 plaques contained papillomavirus DNA sequences from Felis domesticus papillomavirus sequence MY1, and a previously unreported papillomavirus DNA sequence was amplified from 1 plaque. As FdPV-2 was consistently present within the plaques, this suggests that this papillomavirus is the likely etiologic agent. Feline viral plaques can undergo neoplastic transformation to Bowenoid in situ carcinomas (BISCs). As FdPV-2 DNA is frequently present within BISCs, this suggests that FdPV-2 induces viral plaque formation and then remains detectible after neoplastic transformation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21088180/