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Peer-reviewed veterinary case report

CT scan shows liver cancer signs in 4-year-old French Bulldog

By Sim, Hyeonji et al.·Published in Veterinary medicine and science·2025·Department of Veterinary Medical Imaging, South Korea·View original on PubMed

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Original publication title: Contrast-Enhanced Computed Tomography Imaging Features of Primary Hepatic Neuroendocrine Carcinoma in a 4-Year-Old French Bulldog.

Species:
dog

Plain-English summary

A 4-year-old female spayed French bulldog was brought to the vet because she was not eating, seemed very tired, and was vomiting. An ultrasound of her abdomen showed several unusual nodules in her liver, and a CT scan confirmed these nodules were present. A biopsy revealed that she had primary hepatic neuroendocrine carcinoma, a type of liver cancer. This case highlights the importance of considering this cancer when similar liver nodules are found in dogs.

People also search for: French bulldog vomiting · dog liver cancer symptoms · canine anorexia treatment

Abstract

A 4-year-old female-spayed French bulldog presented with symptoms of anorexia, lethargy and vomiting. Abdominal ultrasonography revealed multiple coalescing hyperechoic nodules in the liver. Single-phase contrast-enhanced computed tomography (CT) scan showed heterogeneous liver lobes with hyperattenuating parenchyma and multiple hypoattenuating lesions in the post-contrast phase. No other primary neoplastic lesions were observed. Laparoscopic liver biopsy, histopathology and immunohistochemistry confirmed primary hepatic neuroendocrine carcinoma (PHNEC). Consequently, in cases where multiple hyperechoic nodules on ultrasound and hypoattenuating nodules on post-contrast CT are observed in the liver, PHNEC should be considered as a differential diagnosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40747860/